Titanium dioxide helps protect the skin from both UVA and UVB rays. Plus, it’s generally considered to be safe for sensitive skin types. Not only that, but it might also make for sunscreens that are more suitable for children and infants since it’s much less likely to cause stinging compared to chemical sunscreens. And when used in foundations, titanium dioxide can even provide a little extra sun protection on top of your daily SPF.

Lithopone B301, Lithopone B311 powder, C.I. Pigment White 5, is a mixture of inorganic compounds, widely utilized as a white pigment. It is composed of a mixture of barium sulfate and zinc sulfide. These insoluble compounds blend well with organic compounds and confer opacity. Lithopone B301, Lithopone B311 powder is famous for the cheap production costs, greater coverage. Related white pigments include titanium dioxide, zinc oxide (zinc white), and zinc sulfide

In the application of lithopone in ink industry, lithopone has fine particles, loose structure, good fineness and good paint adhesion, so it can be well combined with other colors in the composition of ink.

Example of partial substitution of titanium dioxide with lithopone supplier 30% in a white masterbatch 

This route affords a product that is 29.4 wt % ZnS and 70.6 wt % BaSO₄. Variations exist, for example, more ZnS-rich materials are produced when zinc chloride is added to the mixture of zinc sulfate and barium sulfide.

Lithopone is added to plastic resin systems to enhance UV protection of the final plastic products that includes outdoor plastics and automotive plastics. It is used as a white pigment for plastics such as polyolefin, vinyl resin, ABS resin, polystyrene, polycarbonate, nylon, and polyoxymethylene (POM). It ensures that UV rays do not penetrate and damage the product and its appearance.  

Titanium dioxide remains in many food products in this country because of regulatory folly by the Food and Drug Administration, which allows problematic food ingredients to remain undetected and unreviewed.

Lithopone 30% is the perfect solution for partial substitution of TiO2 in fillers due to its very soft nature and hardly any shrinkage properties. 

The most significant uncertainty identified by the EU experts was the concern that TiO₂ particles may have genotoxic effects. Genotoxicity refers to the ability of a chemical to directly damage genetic material within a cell (DNA), which may lead to cancer in certain situations. Although the experts did not conclude that TiO₂ particles in E171 are genotoxic, they could not rule out the concern that they might be.

Different dermal cell types have been reported to differ in their sensitivity to nano-sized TiO₂ . Kiss et al. exposed human keratinocytes (HaCaT), human dermal fibroblast cells, sebaceous gland cells (SZ95) and primary human melanocytes to 9 nm-sized TiO₂ particles at concentrations from 0.15 to 15 μg/cm² for up to 4 days. The particles were detected in the cytoplasm and perinuclear region in fibroblasts and melanocytes, but not in kerati-nocytes or sebaceous cells. The uptake was associated with an increase in the intracellular Ca²⁺ concentration. A dose- and time-dependent decrease in cell proliferation was evident in all cell types, whereas in fibroblasts an increase in cell death via apoptosis has also been observed. Anatase TiO₂ in 20–100 nm-sized form has been shown to be cytotoxic in mouse L929 fibroblasts. The decrease in cell viability was associated with an increase in the production of ROS and the depletion of glutathione. The particles were internalized and detected within lysosomes. In human keratinocytes exposed for 24 h to non-illuminated, 7 nm-sized anatase TiO_2, a cluster analysis of the gene expression revealed that genes involved in the “inflammatory response” and “cell adhesion”, but not those involved in “oxidative stress” and “apoptosis”, were up-regulated. The results suggest that non-illuminated TiO₂ particles have no significant impact on ROS-associated oxidative damage, but affect the cell-matrix adhesion in keratinocytes in extracellular matrix remodelling. In human keratinocytes, Kocbek et al. investigated the adverse effects of 25 nm-sized anatase TiO₂ (5 and 10 μg/ml) after 3 months of exposure and found no changes in the cell growth and morphology, mitochondrial function and cell cycle distribution. The only change was a larger number of nanotubular intracellular connections in TiO₂-exposed cells compared to non-exposed cells. Although the authors proposed that this change may indicate a cellular transformation, the significance of this finding is not clear. On the other hand, Dunford et al. studied the genotoxicity of UV-irradiated TiO₂ extracted from sunscreen lotions, and reported severe damage to plasmid and nuclear DNA in human fibroblasts. Manitol (antioxidant) prevented DNA damage, implying that the genotoxicity was mediated by ROS.

Avoiding exposure