While the conclusions of the EU expert panel were considered in this report, Health Canada's Food Directorate conducted its own comprehensive review of the available science. This included evaluating new scientific data that addressed some of the uncertainties identified by the EU expert panel and were not available at the time of their review.    

Gravimetric analysis is a method of quantitative chemical analysis in which a substance is converted into a stable compound of known composition, and the mass of this compound is then measured. This technique offers a high level of precision and is particularly useful in determining the concentration of materials within complex mixtures. The gravimetric determination of titanium dioxide typically involves a series of well-defined steps, which include precipitation, filtration, washing, drying, and weighing.

Titanium dioxide is used in a wide range of food products and consumer goods – from candy to sunscreen and house paint. The U.S. Food and Drug Administration maintains that the regulated use of titanium dioxide, specifically as a color additive in food, is safe under some restrictions.

The precipitation of titanium dioxide involves the reaction of titanium sulfate with an alkaline solution to form titanium hydroxide, which is then calcined to produce titanium dioxide. The precipitation process is crucial for achieving the desired particle size distribution, crystallinity, and purity of the final product.

Although barium sulfate is almost completely inert, zinc sulfide degrades upon exposure to UV light, leading to darkening of the pigment. The severity of this UV reaction is dependent on a combination of two factors; how much zinc sulfide makes up the pigments formulation, and its total accumulated UV exposure. Depending on these factors Lithopone B301, Lithopone B311 powder itself may vary in shade over time, ranging from pure white all the way to grey or even black. To suppress this effect, a dopant might be used, like small amount of cobalt salts, which would be added to the formulation. This process creates cobalt-doped zinc sulfide. The cobalt salts help to stabilize zinc sulfide so it will not have as severe a reaction to UV exposure.

It is an anatase titanium dioxide pigment produced by a special process from sulfuric acid. Widely used in PVC pipes, interior coatings, industrial pigments, rubber, leather, polyolefins, Printing ink, plastic, paper, etc.

Although barium sulfate is almost completely inert, zinc sulfide degrades upon exposure to UV light, leading to darkening of the pigment. The severity of this UV reaction is dependent on a combination of two factors; how much zinc sulfide makes up the pigments formulation, and its total accumulated UV exposure. Depending on these factors the pigment itself can vary in shade over time, ranging from pure white all the way to grey or even black. To suppress this effect, a dopant may be used, such as a small amount of cobalt salts, which would be added to the formulation. This process creates cobalt-doped zinc sulfide. The cobalt salts help to stabilize zinc sulfide so it will not have as severe a reaction to UV exposure.