- Titanium oxide, also known as TiO2, is a widely used inorganic compound that is found in a variety of products and applications. It is commonly used as a pigment in paints, plastics, papers, and other materials due to its excellent opacity and durability. Titanium oxide is also utilized in the production of sunscreen, as it provides a high level of UV protection.


For those wishing to limit or avoid exposure to titanium dioxide in foods, there are some steps you can take.
What are the forms of titanium dioxide?
Lithopone(CAS NO.1345-05-7) is manufactured by a process in which barium sulfide solution is prepared by reducing barite ore (BaSO4) with carbon and leaching the resulting mass.
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A study published in the Journal of Agricultural and Food Chemistry in 2019 sought to examine the effects of titanium dioxide on intestinal inflammation. Researchers did this by feeding rats titanium dioxide nanoparticles and found that, after the course of two to three months, the animals had lower body weights and induced intestinal inflammation. The researchers also found the nanoparticles altered gut microbiota composition and aggravated chronic colitis. The rats also experienced reduced populations of CD4+T cells (which are cells that help organize immune responses by prompting other immune cells to fight infection), regulatory T cells, and white blood cells in mesenteric lymph nodes. The researchers wrote: “Dietary TiO2 nanoparticles could interfere with the balance of the immune system and dynamic of gut microbiome, which may result in low-grade intestinal inflammation and aggravated immunological response to external stimulus, thus introducing potential health risk.”
THE OBSCURE HISTORY OF A UBIQUITOUS PIGMENT: PHOSPHORESCENT LITHOPONE AND ITS APPEARANCE ON DRAWINGS BY JOHN LA FARGE
Characterization of vitamins@P25TiO2NPs

Titanium Dioxide DongFang R5566 Tio2 Powder
In a 2016 study published in Scientifica (Cairo), Egyptian researchers examined the effects of titanium dioxide nanoparticles on the organs of mice by orally administering the food additive daily, for five days. The results showed that the exposure produced “mild to moderate changes in the cytoarchitecture of brain tissue in a time dependent manner.” Furthermore, “Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of Alzheimer’s disease.” The researchers wrote: “From these findings, “the present study concluded that TiO2NPs is genotoxic and mutagenic to brain tissue which in turn might lead to Alzheimer’s disease incidence.”
The so-called “barrier effect” makes it possible to achieve good anti-corrosion protection in primers.
Calcium carbonate and titanium dioxide are two important minerals that are widely used in various industries. While they share some similarities, they also have distinct differences when it comes to their manufacturing processes and applications.
Total Zinc (as ZnS)